Fallout is Dead. Long live Fallout.
People have been saying Fallout is dead since the 2nd game. The series is still around and still has entertainment value. This isn't even a proper sequel so it doesn't really matter what they do in the scheme of things.
It's retarded that they got stuff like Deathclaws and Super Mutants this early in the game setting, but Bethesda doing retarded shit is pretty standard now. I'm going to guess Bethesda's just going to retcon the lore at this point which was probably inevitable.
Personally, I'm not going to nerd rage about this. I will probably be taking the "wait and see" approach since I figure Bethesda's going to roll out this game with a shitload of bugs anyway.