Last year, I played an absolute shitload of it on that online version of Yu-Gi-Oh (can't remember the name of it), as well as with my one friend who actually had cards irl. It's really quite enjoyable, especially when you get to decimate your enemies with three Blue-Eyes :P Although I don't really like modern Yu-Gi-Oh so much. Too much bullshit summoning which makes the game too predictable.
I had a game when I was, like, 7; in fact it's still in my cupboard XD But I can't play it because I don't have a Game Boy. I liked the TV show, though after the first season (with Yugi and Kaiba), I didn't see it. Also, abridged! :P