Well, considering the fact that not all of the interruptions were legitimate corrections, and a lot were just either insults or irrelevant (IE, "Oh, you're Jack Kennedy now?"), and so it turned me off. I mean, you have to admit that 87 interruptions in a 90 minute debate is a little excessive. Also, I didn't catch that many lies from Ryan, but I did from Biden. Ryan did a good job of pointing out the lies, but I wish he did a better job with the contradictions.
The issue I think Ryan did the worst on (remember I'm doing this from pure memory, so I could be wrong) was on relations in the Middle East. He was floundering around and started just becoming redundant, so everybody could tell that he wasn't prepared on the issue. What I think he did best on was his attack on the President's claim that the rich have to pay "a little more" to get the economy back on track by stating that even if he raised income taxes on that demographic to 100%, it couldn't cover the Obama administration's spending.
I didn't commit Biden's portions to memory as I was observing Ryan (I wanted to see how he could handle himself in his first debate) for the most part, but if you bring up a few things I can tell you my opinion by memory.