I found his video very pessimistic. I don't think that bots will eventually take all of the jobs as that wouldn't be beneficial for anyone (with the possible exception of the bot-sellers). If 45% of the population will become jobless the economy would collapse, as that'll mean that the government will receive much less taxes long-term. I don't think any government, not union, nor reasonable person would allow that.
Furthermore, CGP Grey is in my recollection mostly talking about money as the motivation for automation, but I don't think that it is. There are a lot of people who love their jobs, and that is, in my opinion, a great motivation to not automate as people will always find a way to do a job they like, even if there is a cheaper alternative in automation.
Automation also costs tons of money, and in the foreseeable future, I don't think that companies will employ bots on a massive scale as that will cost millions or billions in a short amount of time. You can already see this in the present. Take China for example, the reason that millions of unskilled laborers still find work there is the simple fact that automation costs too much money.
However, I agree with CGP Grey that some forms of work will inevitably be automated, like parts of the delivery sector. However, I still believe that full automation of most forms of work will happen, as that would mean that large parts of society would become jobless, which would in my opinion mean that society will be disrupted in an unprecedented scale, which a government won't let happen.